水迷宫

2010年12月10日 | 标签:

《血型和性格》写了点,可发现写不下去,早知道当初就不计划写这部分的内容了。只要你搜搜,就能看到很多八卦血型与性格、爱情的文字,看不看我的,其实真的无所谓。连方舟子还写过一个血型系列,当然写得不错,看过才知道,原来顶级的自然科学杂志《nature 》还刊过几篇研究血型与性格方面是否有联系的论文

自己写不下去的另一个原因就是,不敢花时间去写,因为每天要保证足够的睡眠。这些日子上班还是很忙的,休息时还得做会儿实验。比如今天下夜班,昨夜也没躺几个小时,一直忙到中午11点才下班,下午回来就直接来到动物房,给老鼠做水迷宫实验

水迷宫实验还是比较好玩的。它是一个很简单的装置,通过连接电脑的摄像头拍摄老鼠在水盆里寻找水面下的平台的轨迹,来分析老鼠的学习和记忆能力

装置如下图:

开始实验时,这个帘子得拉上,不让老鼠看到周围的环境,避免老鼠通过四周的景物来定位

(灌水)

(整个盆底是黑色的,平台也是黑色的,水面超过平台后,平台就看不出来了)

生后42天的老鼠,这种老鼠又称SD大鼠(rat),和另一种实验常用的小鼠(mouse)是不同的。这些42天的rat是很文静的,就是把笼子的盖打开,它们也只是探头张望,不敢跑出去

把老鼠丢进水里,它就开始游泳。每次实验2分钟,第一次入水的老鼠是很难找到水面下的平台的。往往2分钟到的时候,它还在游泳,而且只会贴着水盆的边缘游(它们也许认为由此可以登陆的)。于是我们就用棍棒指引它游到平台上,上了平台,它就可以休息了(算是刺激了它的奖赏系统),聪明的老鼠很快就能学会定位平台的位置,隔一段时间,再把它丢进水里,它能在20秒内上台。而大脑受损的老鼠,总是记不住,不管你怎么教它,它只会贴着水盆的边缘游,结果累得眼睛都睁不开了,不把它捞出来,就会溺死的;还有个别笨老鼠,今天你教它一次,第二次下水,它也能找到平台,可要多花几十秒钟。但第二天再下水,它又忘了,又得重新教。而那些聪明的老鼠,第二天依然可以迅速的上台

这个实验连作四天,最后一天的设计最绝,可以看出人类有多么坏。那就是把水面下的平台偷偷的拆了,然后把老鼠放进水里。只见那些老鼠只在有平台的那个象限不停的穿越,苦苦地执着地寻找那已不存在的休息之地。水盆上的摄像机一直会拍摄老鼠们的游泳轨迹,软件会自动分析它们的登台时间、穿越象限的次数等等数据,这些数据最终反映不同状态下的老鼠的学习和记忆能力。本来准备贴几张有趣的轨迹图给各位猎奇一下,可我师妹说了,接水迷宫的电脑有毒,而这几天我的电脑的杀毒软件也不工作了,保险起见,就不贴了

明天本该休息,但别人和我换班,所以明天又得早起,而间接的好处是我获得了周日和周一的连休。明晚的这个时侯,我会在干净的列车上构想如何去写《血型和性格》

还有,别忘了,今天是12月10号。现在的奥斯陆正在颁奖吧,一个华裔小提琴家将会在现场演奏那优美的《茉莉花》。当然,现场将会有一个空位

≈≈≈≈≈≈

刚刚看到文字直播,张wan钧还演奏了《彩云追月》和《爱的礼赞》 :)

其后是挪威女演员乌曼朗读:在我已过半百的人生道路上,1989年6月是我生命的重大转折时刻……

  1. 大宝
    2010年12月10日23:02

    盐湖阿盐湖你可真够坏的!

  2. 民老头
    2010年12月11日00:34

    医生非常辛苦,好好休息,血型与性格不用写了,不靠谱。
    我刚带儿子看病回来,协和的大夫人很好。
    我们会看到他去补领这个奖,一定会的。

  3. 小师妹
    2010年12月11日10:52

    “只见那些老鼠只在有平台的那个象限不停的穿越,苦苦地执着地寻找那已不存在的休息之地。”可见经验有时并不可靠。所以也有了守株待兔的故事。

    这个实验真有意思,比弄死那些小白鼠要略微不残忍一些。但谁能说清楚生理折磨和精神折磨哪个残忍哪个不残忍呢

  4. yanhu
    2010年12月14日20:17

    @大宝

    在形形色色的老鼠实验中,水迷宫还算是仁慈的

    真的佩服那个设计把平台拆下的人,真的很坏很聪明,我目前还坏不到那个地步

  5. yanhu
    2010年12月14日20:32

    @民老头

    《血型和性格》还要写,但我准备换个方式写。怎么写?基本上想好了

    谢谢你对医生的评价。半夜看病回来,家长和孩子也很辛苦啊

    昨晚在列车上,突然听到前座的一个青年女子问身边的一个五十岁出头的男人:你知道刘XB是谁吗? 我起身一看,原来她在看《新闻晨报》,一篇报道说西方借诺贝尔和平奖打压中国。 旁边的那个老男人的回答太让我失望:估计是和疆独、藏独有关的人。我在后面一排,心里面那个急啊,真想告诉她刘XB是谁,可我和她不是一排,犹豫了1分钟,该不该插手别人之间的谈话,最后还是决定放弃这次公共场合上的答疑

    我想我们应该会看到崩溃之日的,那将是何等的激动人心 :)

  6. yanhu
    2010年12月14日20:44

    @小师妹

    很多实验的设计是很有意思的,只是没人愿意用简单的语言把它们讲出来

    人有时是虚伪的,弄死一只实验中的老鼠、实验中的猫、实验中的狗,就要被谴责

    而你在吃美味的虾、鱼……等等等等动物时,怎么没有自责?

    记得曾经考试时的一篇阅读理解,很多人在实验室外抗议用动物做实验。实验人员就解释:你们可知道,用于人类的疫苗,实验阶段必须经过动物实验环节的,我们这里的所有动物实验的最终目的都是为人类的健康服务的

    当然,目前实验机构都有动物伦理委员会,负责审批动物实验的设计,避免过于残忍的idea,但国内的动物伦理委员会多是摆设。因为,因为,因为我们的人的伦理问题还没解决

  7. 会长胖
    2010年12月15日01:02

    谢谢yanhu的这篇文.
    借此说一点与医学试验完全无关的我对人类吃肉的一点想法.
    人要吃肉,并喜欢吃好吃的肉,这是自然的本能的.
    我不反对吃牛吃鱼吃鸡等等等等.虽然我本人一定不会吃猫肉狗肉,但是我觉得没有
    理由反对有些人吃猫吃狗.
    但是,有些人类吃灵长目的动物,这个我无论如何不能接收. 这是我想说的第1点.
    都是吃肉,怎么吃,或者说怎么宰杀,怎么处理动物,我觉得是很重要的.
    一些人(特别是亚洲的一些人)就是认准了鲜活的东西最好吃(且不说这个观点未必正
    确 – 这不是我要讨论的方向),所以她们处死动物,经常有千奇百怪的残忍的方式.
    我非常的不能接收.
    还有一个例子,人类吃鱼翅,真的很残忍. 假设说鲨鱼肉很鲜美,人类捕食鲨鱼,为的
    吃肉的话,只要不是过度捕食,我也不会反对.但是,每年有将近1000条鲨鱼,被打捞上
    船,割掉鳍,然后再活生生扔回海里,真是海洋的灾难.如果持续下去,也必将是人类和
    地球的灾难.
    写到这里,我忽然想,虽然我已经在泡网提过好几次鱼翅这个事情,但是,也许应该认真地
    专门写一篇关于鱼翅的文章…

  8. yanhu
    2010年12月15日20:18

    @会长胖

    谢谢你写了这么多

    关于你刚刚提到的这个问题,我准备写上一篇,题目可能是《食物、虚伪及其它》

    但今晚我已经写了一篇,不能花时间再写了,明晚夜班,后天贴出来

  9. YU
    2010年12月20日15:19

    帝都更帝都,百姓更百姓,真实感受。

  10. yanhu
    2010年12月20日19:17

    @YU

    为了了解您这句留言的意思,我猥琐的查了一下你的IP

    原来你的休假结束了,真的很短

    难道这就是你这段时间返家后的感受?

  11. YU
    2010年12月21日08:54

    @yanhu

    嗯,你冰雪。字里行间让我想起朝廷,所以感慨一下。

  12. yanhu
    2010年12月21日14:05

    @YU

    还是不得不问一句

    “我冰雪”是什么意思?(不是懂装不懂:))

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